NATURAL ANTIDEPRESSANT REMEDIES
(Monoamine oxidase inhibitors (MAOIs)
What are monoamine oxidase inhibitors (MAOIs)?
They are products that inhibit the action of the enzyme monoamine oxidase (MAO).They are used as a kind of medicines for the treatment of depression.
There are two types of MAOIs:
- MAO- A: (Such as Brofaromine, Minaprine or Toloxatone) They act on melatonin, serotonin, dopamine, epinephrine and norepinephrine.
- MAO- B: (Such as Rasagiline or Lazabemide) They act on dopamine, phenylethylamine and trace amines
Some MAOIs can act in both groups. They are called nonselective MAO-A/MAO-B Inhibitors, for example: Pheniprazine, Isocarboxazid, Benmoxin or Furazolidone.
They are only used a a last resort when other treatments fail because they can interact with certain foods or with other medicines.
Dangers of monoamine oxidase inhibitors
- They inhibit inhibit the catabolism of dietary amines. For example, they react with food containing tyramine, so they can produce hypertensive crisis. Tyramine is an amine that derives from the amino acid tyrosine. Foods containing tyramine are:
- Smoked, pickled, spoiled, fermented or processed meat. Liver, pork, except cured ham.
- Fermented food:cheese, yogurt, soy sauce, tofu, yeast, shrimp paste, etc.
- Alcoholic beverages
- They can interact with other medicines, herbal remedies, drugs or supplements. So, it is necessary for the patients to know which medicines should avoid.
- They may have dependence producing effects, so they can not be discontinued abruptly.
Monoamine oxidase inhibitors (MAOIs) in herbal remedies
Many herbal remedies contain MAOIs. The following list does not refer to all of them, so you should consult your doctor or specialist before undertaking any herbal medication, specially if you are taking any type of medication or you have a very rich anime diet.
More information about natural medicine in the listing above.
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This material is for informational purposes only. In case of doubt, consult the doctor.