Natural antidepressant remedies from plants

(Monoamine oxidase inhibitors (MAOIs)

What are monoamine oxidase inhibitors (MAOIs)?

They are products that inhibit the action of the enzyme monoamine oxidase (MAO).They are used as a kind of medicines for the treatment of depression.

There are two types of MAOIs:

  • MAO- A: (Such as Brofaromine, Minaprine or Toloxatone) They act on melatonin, serotonin, dopamine, epinephrine and norepinephrine.
  • MAO- B: (Such as Rasagiline or Lazabemide) They act on dopamine, phenylethylamine and trace amines

Some MAOIs can act in both groups. They are called nonselective MAO-A/MAO-B Inhibitors, for example: Pheniprazine, Isocarboxazid, Benmoxin or Furazolidone.

They are only used a a last resort when other treatments fail because they can interact with certain foods or with other medicines.

Dangers of monoamine oxidase inhibitors

  • They inhibit inhibit the catabolism of dietary amines. For example, they react with food containing tyramine, so they can produce hypertensive crisis. Tyramine is an amine that derives from the amino acid tyrosine. Foods containing tyramine are:
  • Smoked, pickled, spoiled, fermented or processed meat. Liver, pork, except cured ham.
  • Fermented food:cheese, yogurt, soy sauce, tofu, yeast, shrimp paste, etc.
  • Alcoholic beverages
  • Brazil nuts, bananas, raspberries, pineapple, eggplants, figs, avocados, red plums, peanuts, coconuts
  • In combination with foods containing much tryptophan, they can produce serotonin syndrome. (See tryptophan foods)
  • They can interact with other medicines, herbal remedies, drugs or supplements. So, it is necessary for the patients to know which medicines should avoid.
  • They may have dependence producing effects, so they can not be discontinued abruptly.

Monoamine oxidase inhibitors (MAOIs) in herbal remedies

Many herbal remedies contain MAOIs. The following list does not refer to all of them, so you should consult your doctor or specialist before undertaking any herbal medication, specially if you are taking any type of medication or you have a very rich anime diet.

PlantprincipleMAOIs type
Agrimony (Agrimonia eupatoria)Quercetin / Quercitrin / apigenin/ KaempferolMAO-A inhibitors
Angelica (Angelica archangelica)PsoralenMAO-A Inhibitors
Ayahuasca (Banisteriopsis caapi)Harmala alkaloidMAO-A/MAO-B Inhibitors
Bearberry (Arctostaphylos uva-ursi)Quercetin / Quercitrin / tannin/MAO-A/MAO-B Inhibitors
Bai Zhi (Angelica dahurica)PsoralenMAO-A Inhibitors
Barberry (Berberis vulgaris)BerberineMAO-A Inhibitors
Bilberry (Vaccinium myrtillus)Quercetin / Quercitrin /MAO-A/MAO-B Inhibitors
Cat’s claw (Uncaria tomentosa)Catechin /EpicatechinMAO-B inhibitors
Caraway (Carum carvi)Quercetin /Kaempferol/ Tannin/ Scopoletin / Myristicin
Carrot (Daucus carota)PsoralenMAO-A Inhibitors
Celery (Apium graveolens)PsoralenMAO-A Inhibitors
Cocoa (Theobroma cacao)Catechin /EpicatechinMAO-B inhibitors
Coriander (Coriandrum sativum)PsoralenMAO-A Inhibitors
Evening-Primrose (Oenothera biennis)QuercetinMAO-A inhibitors
Coffee (Coffea arabica)Harmala alkaloidMAO-A/MAO-B Inhibitors
Coptis chinensisBerberine /CoptisineMAO-A Inhibitors
Fennel (Foeniculum vulgare)PsoralenMAO-A Inhibitors
Echinacea (Echinacea ssp.)QuercetinMAO-A/ MAO-B Inhibitor
Ginger (Zingiber officinale)QuercetinMAO-A/ MAO-B Inhibitor
Gingkgo (Ginkgo biloba)Quercetin / Quercitrin / apigenin/ isorhamnitin / KaempferolMAO-A/MAO-B Inhibitors
Gentian (Gentiana lutea)Isogentisin / Tannin/ MangiferinMAO-B inhibitors
Goldenseal (Hydrastis canadensis)BerberineMAO-A Inhibitors
Himalayan Mayapple Podophyllum hexandrumQuercetinMAO-A/ MAO-B inhibitors
Horse chestnut (Aesculus hippocastanum)Quercetin / Quercitrin /scopoletin/ tannin /KaempferolMAO-A /MAO-B Inhibitors
Huang-Lia (Coptis japonica)BerberineMAO-A Inhibitors
Javan Turmeric (Curcuma xanthorrhiza)CurcuminMAO-A/MAO-B Inhibitors
Kiwi (Actinidia chinensis)QuercetinMAO-A/ MAO-B Inhibitors
Lovage (Levisticum officinale)PsoralenMAO-A Inhibitors
Licorice (Glycyrrhiza glabra)Quercetin/ apigenin/ genistein/ Glycyrrhizin //KaempferolMAO-A/MAO-B Inhibitors
Marshmallow (Althaea officinalis)Quercetin/ tannin/ scopoletin/KaempferolMAO-A/MAO-B Inhibitors
Mayapple (Podophyllum peltatum)QuercetinMAO-A/ MAO-B inhibitors
Onion (Allium cepa)QuercetinMAO-A/ MAO-B inhibitors
Pansy (Viola tricolor)QuercetinMAO-A/ MAO-B inhibitors
Parsnip (Pastinaca sativa)Psoralen / Quercetin / myristicin/ Kaempferol / isoharmetinMAO-A/ MAO-B inhibitors
Parsley (Petroselinum crispum)PsoralenMAO-A Inhibitors
Passion flower (Passiflora spp.)Harmala alkaloidMAO-A/MAO-B Inhibitors
Prickly Poppy (Argemone mexicana)BerberineMAO-A Inhibitors
Red grapes (Vitis vinifera)ResveratrolMAO-A Inhibitors
Rue (Ruta graveolens)Psoralen/ quercetin/scopoletinMAO-A/MAO-B Inhibitors
Shoti (Curcuma zedoaria)CurcuminMAO-A/MAO-B Inhibitors
St John’s wort (Hypericum perforatum)Quercetin / Quercitrin /Hypericin/ Kaempferol/ Scopoletin/ XhantonesMAO-A/MAO-B Inhibitors
Stinktree (Ailanthus altissima)QuercetinMAO-A Inhibitors
Syrian rue (Peganum Harmala)Harmala alkaloidMAO-A/MAO-B Inhibitors
Strawberry (Fragaria vesca)Quercetin / Quercitrin// Kaempferol/tanninMAO-A/MAO-B Inhibitors
Tea (Tea sinensis)Catechin / EpicatechinMAO-B inhibitors
Tribulus terrestrisHarmala alkaloid /Harmine/ HarmalolMAO-A/MAO-B Inhibitors
Tobacco (Nicotiana tabacum)Harmala alkaloid /Harmine/ HarmalolMAO-A/MAO-B Inhibitors
Turmeric (Curcuma longa)CurcuminMAO-A/MAO-B Inhibitors
Valerian (Valeriana officinalis)QuercetinMAO-A/ MAO-B inhibitors
Yarrow (Achillea millefolium)Quercetin /Quercitrin/apigenin/ isorhaamnetinMAO-A /MAO-B Inhibitors

punto rojoMore information about plant-based food nutrients

Written by Editorial Botanical-online team in charge of content writing

26 September, 2022

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